LSD was first synthesized November 16, 1938 by Swiss chemist Albert Hofmann at the Sandoz Laboratories in Basel, Switzerland as part of a research program for medically useful ergot, a fungus that grows on rye and other grains, alkaloid derivatives. LSD's psychedelic properties were discovered 5 years later when Hofmann accidentally ingested the chemical. The first intentional ingestion of LSD occurred on April 19, 1943, when Hofmann ingested 250 µg of LSD. He said, this would be a threshold dose based on the dosages of other ergot alkaloids. Hofmann found the effects to be much stronger than anticipated. Sandoz Laboratories introduced LSD as a psychiatric drug in 1947.
Skeletal formula and ball-and-stick and space-filling models of the lysergic acid diethylamide (LSD) molecule, C20H25N3O.
* Carbon, C: grey-black
* Hydrogen, H: white
* Nitrogen, N: blue
* Oxygen, O: red
Image generated in Accelrys DS Visualizer. Date: 13 March 2011(2011-03-13) Author: Ben Mills.
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TEXT RESOURCE: Lysergic acid diethylamide